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Home/ Questions/Compare and contrast serine proteases and aspartic proteases.
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kttutoria
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kttutoriaExpert
Asked: April 13, 20222022-04-13T03:22:07+00:00 2022-04-13T03:22:07+00:00In: Biology

Compare and contrast serine proteases and aspartic proteases.

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Compare%20and%20contrast%20serine%20proteases%20and%20aspartic%20proteases.%20Not%20all%20answers%20will%20be%20used.%20Question%203...

Compare and contrast serine proteases and aspartic proteases. Not all answers will be used. 

Serine protease Both Aspartic protease
  •  direct electrophilic attack by water
  • covalent intermediate
  • tetrahedral intermediate
  • trigonal planar intermediate
  • catalytic triad of serine, leucine, and valine
  • four aspartic acids in active site
  • catalytic triad of serine,histidine, and aspartic acid
  • direct nucleophilic attack by water
  • two aspartic acids in active site

♦ Relevant knowledge
Protease enzymes are a type of enzyme which has the catalytic role of hydrolysis of the peptide bond within proteins. Protease enzymes are found in the small intestine.

proteases
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    kttutoria Expert
    2022-04-21T14:44:29+00:00Added an answer on April 21, 2022 at 2:44 pm
    Serine protease Both Aspartic protease
    • catalytic triad of serine,histidine, and aspartic acid
    • covalent intermediate
    • tetrahedral intermediate
    • direct nucleophilic attack by water
    • two aspartic acids in active site
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  2. Emma Wilson
    2022-04-13T03:22:15+00:00Added an answer on April 13, 2022 at 3:22 am

    Serine protease
    – The catalytic trio of serine and histamine.
    – Covalent intermediate
    Both:
    – Water can directly nucleophilic attack
    – Tetrahedal intermediate
    Aspartic Protease
    – 2 aspartic acid in active site

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  3. Ava Smith
    2022-04-13T03:22:18+00:00Added an answer on April 13, 2022 at 3:22 am

    Except for the direct nucleophilic attack of water, the first two answers are correct.

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  4. Alexander Roberts
    2022-04-13T03:24:36+00:00Added an answer on April 13, 2022 at 3:24 am


    Compare%20and%20contrast%20serine%20proteases%20and%20aspartic%20proteases.%20Not%20all%20answers%20will%20be%20used.%20Question%203...

    Serine protease Two Aspartic protease 2 Aspartic acids in active-site catalytic triad of histidine, serine and aspartic acid covalent intermediate transmembrane tetrahedral direct nucleophilic attacks by water
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  5. Elizabeth Lam
    2022-04-13T03:24:36+00:00Added an answer on April 13, 2022 at 3:24 am


    Compare%20and%20contrast%20serine%20proteases%20and%20aspartic%20proteases.%20Not%20all%20answers%20will%20be%20used.%20Question%203...

    Serine protease Both Aspartic protease covalent intermediate tetrahedral direct nucleophilic water attack by water catalytic triad of serine, histidine and aspartic acid 2 aspartic acids active site
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