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Which of the following statements about the active site of an enzyme is correct?
- A. The active site of an enzyme binds the substrate of the reaction it catalyzes with lower Kd than it does the transition state intermediate
- B. The active site of an enzyme binds the substrate and transition state with equal Ka
- C. The active site of an enzyme binds the product of the reaction it catalyzes higher Ka than it does the transition state intermediate D. The active site of an enzyme is complementary to the substrate of the reaction it catalyzes
- E. The active site of an enzyme binds the substrate of the reaction it catalyzes with higher Kd than it does the transition state
Proteins are the main components of enzymes. Some enzymes also contain components that bind with proteins. An enzyme’s active center is a unique spatial structure that binds with a substrate and catalyzes biological reactions. Mechanism of action At the active site, the enzyme-substrate combination forms. To produce products, enzymes interact with substrates. Each enzyme can only catalyze one type of biochemical process. The enzyme first binds to the substrate at its specific activity center. This creates an intermediate compound (enzyme-substrat) that is compatible with the enzyme. React with the substrate. At the end of the reaction, the compound will be broken down to produce an enzyme that can catalyze a reaction with another substrate of the same type.
The correct answer is E.
Because: enzymes-protein molecules -increase the rate of the reaction
activation energy – minimally required to form the reaction
substrate -> product
enzyme decrease A.E, active site
enzyme active site binds to in substrate with high Kd
Kd is eqilibrinum dissociation constant
Higher Kd means binding is less strong.
Lower Kd means strong the bonding.